Problem formulation. Modern medical technologies aim at personification of the applied medical methods, active use of data on the human genome for treatment and prevention, moving closest possible to the healthy population for diseases prevention. The introduction of such technologies should be regulated by law with due diligence. The main problems here arise when providing free medical care to citizens within the framework of the compulsory health insurance system due to differences in the territorial compulsory health insurance programs and the need, on the one hand, to comply with established standards and treatment protocols, and on the other hand, to consider individual specifics of the patient. A particular scientific task to solve a scientific problem. The aim of the research was to study legal problems that local governments have with the personalized medicine concept implementation while providing free medical care in the frames of the compulsory medical insurance system in the Russian Federation, and ways of solving them. Methodological basis. In the course of the research, the federal and regional legislation of the Russian Federation, regulating the activities of local authorities in the field of healthcare, was studied. Research methods. Formal legal and comparative legal methods, common for legal science, were used in the research. Main research results. As a result of studying the Russian federal and regional legislation, regulating the activities of local bodies in the field of healthcare, the successful practice of applying modern medical technologies in certain RF entities, the specific features of the legal regulation of using the personalized medicine technologies at the local level for treating and preventing diseases was analyzed. The author has proposed specific ways of legal regulation of the step-by-step implementation of personalized medicine at the level of municipal medical facilities.
Conclusions. The introduction of modern technologies of personalized medicine into clinical practice in Russia is constrained for a number of reasons with one of the most important being the imperfection of legal regulation of this field. As a result, the quality and accessibility of medical care provided within the framework of the compulsory healthcare insurance system decreases, the cost of treatment increases, and its efficiency reduces. It is possible to resolve the issue only if the law defining conditions to provide medical care to citizens based on modern genetic research and modern techniques, while maintaining control over the quality of provision, is introduced into the Russian legislation. The result will be budget savings while improving the quality and accessibility of medical care.